Research Core Labs
One of the defining features of a top-tier research university is the availability of core facilities that provide a spectrum of contemporary analytic tools that can be shared across the campus. Ideally these cores provide both technical and consultative services at modest cost and, as a result, elevate the quality of the overall research enterprise. It is appropriate that the core landscape evolves as new technologies emerge and others become obsolete.
Below is a list to the current operational research cores supported by the School of Medicine and the research leadership on the Anschutz Medical Campus.
Core Labs
(Showing all 53 labs)(Clear Search Results)
Allergy and Clinical Immunology Core
Director: Brent Palmer
Technical Director: Charles Preston Neff
Location: RC2, 10th Floor, Room 10231 and 10232
Services: Flow Cytometry, Cellular Immunology, Cell Analysis and Sorting, Monoclonal Antibody Panel Design, Data Analysis
Website: ClinImmune, Allergy & Clinical Immunology, Infectious Disease Flow Cytometry & Bioarchiving Facility
Animal Imaging Shared Resource (AISR) at the CU Cancer Center
Director: Natalie Serkova
Manager: Jenna Steiner
Administrator: Michaela Montour
Location:
RC1 North: Vivarium, P18-0434, P18-0443
RC2: P15-1109, P15-1306, P15-1214
Services: Magnetic Resonance Imaging (MRI), IVIS Imaging, Bioluminescence, Computed Tomography (CT), FDG-PET
Website: Animal Imaging Shared Resource
Anschutz Center for Microbiome Excellence (ACME)
Director: Catherine Lozupone
Technical Director: Nichole Nusbacher
Location: RC1 N, 8th Floor, Room 8119
Services: 16S rRNA targeted sequencing, Microbiome Data Analysis, Nucleic Acid extraction, Bacterial culture
Autoantibody/HLA Core Facility
Director: Liping Yu
Administrator: Allison Reeds
Location: Barbara Davis Center: M20-4201A-H
Keywords: Autoantibodies, HLA, Type 1 diabetes, Celiac disease, Biomarker
Website: Autoantibody/HLA Core Facility
Biostatistics & Bioinformatics Shared Resource (BBSR) at the CU Cancer Center
Biostatistics Director: Dexiang Gao
Biostatistics Manager: Andrew Nicklawsky
Bioinformatics Director: James (Jim) Costello
Bioinformatics Manager: Andrew Goodspeed
Location:
Fitzsimons: Q20-N2211, Q20-N2215, Q20-N2227C^02, Q20-N6203D, Q20-N6203E, Q20-W3127^02
RC1 South: L18-5113^02
Services: Biostatistics, Bioinformatics, Grant preparation and Study design, Data analysis, -omics, Clinical trials
Cardiovascular Bioimaging Core: CTRC Outpatient Clinic
Director: Kerrie Moreau
Administrator: Tim Lockie
Location: Anschutz Health Sciences Building (AHSB) 6th Floor - CTRC Outpatient
Services: Ultrasound, Cardiac, Vascular, Liver, Fibroscan
Cell Technologies Shared Resource (CTSR)
Director: Peter Dempsey
Manager: Anh Le
Location: RC1 South: L18-5404B
Services: Hybridoma/Monoclonal antibody, Fetal calf serum, Cell lines, Protein expression, IncuCyte
Website: Cell Technologies Shared Resource
Center for Innovative Design and Analysis (CIDA) - Consulting Center
Director: Nichole Carlson (CSPH)
Consulting Center Manager: Camille Hochheimer
Administrator: Theresa Jennings
Location: Fitzsimons: 4th Floor West
Services: Data Analysis, Grant Development and Study Design, Data Science, Biostatistics, Long/Short-Term Partnerships
Clinical Research Support Team (CReST)
Director: Benjamin Echalier
Location: Fitzsimons Building, WG109
Services: Clinical Coordinators & Coordination, Clinical Monitoring, IRB & Regulatory Assistance, Study Startup & Administration Help, OnCore Submission & Signoff Help, Sponsor Invoicing, Invoice Payments
Colorado Anschutz Research Genetics Organization (CARGO)
Principal Investigator: Kathleen Barnes
Director: Monica Campbell
Project Managers: Meher Boorgula, Nicholas Rafaels
Administrator: Alesia El Ali
Location: RC2: P15-3490B, P15-3490C, P15-3490F
Services: DNA/RNA Services, Genotyping, Data Analysis
Website: Colorado Anschutz Research Genetics Organization (CARGO)
Colorado Clinical and Translational Sciences Institute (CCTSI) Clinical Research Core: Adult CTRC Core Laboratory
Manager: Rebecca Baldermann
Administrator: Tim Lockie
Location: Anschutz Health Sciences Building (AHSB) 6th Floor, Room 6110
Services: Research Laboratory, Analytical Testing, Chemistry Testing, Hormone/Peptide Testing, Cytokine Testing, Immunological Testing, HPLC, ELISA, RIA, COVID Testing, CAP and CLIA Accreditation Lab
Website: CTRC Services
Colorado Clinical and Translational Sciences Institute (CCTSI) Clinical Research Core: Biostatistics, Epidemiology, and Research Design (BERD)
Director: Nichole Carlson
Administrator: Theresa Jennings
Location: Fitzsimons: 4th Floor West
Services: Grant Development, Data Analysis, Statistical Education, Long/Short-Term Partnerships
Website: Biostatistics, Epidemiology and Research Design (BERD)
Colorado Clinical and Translational Sciences Institute (CCTSI) Clinical Research Core: CTRC Nutrition Services
Director: Janine Higgins
Manager: Tyson Marden
Administrator: Tim Lockie
Location: Kitchen in AHWC: 1st floor; Office/Clinic in AHSB: Room 6023
Services: Nutrition, Dietary intake, Metabolic meals, Diet design, Measurement of habitual dietary intake
Website: Nutrition Services
Diabetes Research Center Bioresources Core
Director: Lori Sussel
Administrator: Mark Farrell
Location: Barbara Davis Center: M20-4207 and M20-4209
Services: Islet isolation/function, Cytometry, Microscopy, Sanger sequencing, STR profiling
Website: Core Facilities
Drug Discovery and Development Shared Resource (D3SR) at the CU Cancer Center
Director, Arm 1: Dan LaBarbera (Drug Discovery and Hit-to-lead Drug Development)
Director, Arm 2: Dan Gustafson (In Vivo Pharmacology)
Pharmacology Manager: Krista Banks
High-throughput Screening Manager: Qiong Zhou
Location: Flint Animal Cancer Center, CSU School of Pharmacy
Services: Drug discovery, Pharmacokinetic and pharmacodynamic modeling, High throughput and high content sequencing, Compound libraries, Metabolism, Drug transporter studies
Website: Drug Discovery and Development
Electron Microscopy Core Facility
Director: Anza Darehshouri
Administrator: Kate Beatty
Location: RC1 South 1207
Services: Electron microscopy, Project consultation, Sample preparation, Sample analysis, Training
Website: Electron Microscopy Core Facility
Flow Cytometry Shared Resource (FCSR) at the CU Cancer Center
Director: Eric Clambey
Manager: Christine Childs
Administrator: Michaela Montour
Location: RC1 South: L18-4112, L18-4204, L18-4208, L18-4215, L18-4402G and RC1 North: P18-8207
Services: Flow cytometry, Cell sorting, CyTOF, Spectral flow cytometry, Mass cytometry
Core-Specific Equipment: Beckman Coulter MoFlo Astrios, MoFlo XDP Flex, Sony MA900, Miltenyi Biotec Tyto, BD Fortessa, Cytek Aurora, Cytek Northern Lights, Agilent Novocyte Penteon, Propel Yeti, BioRad ZE5, Gallios 561, CyTOF XT, Vi-CELL BLU, Antibody bank, FlowJo, FCS Express, Cell Engine, Kaluza, ModFit, Astrolabe
Website: Flow Cytometry
Functional Genomics Shared Resource (FGSR) at the CU Cancer Center
Director: Joaquin Espinosa
Manager: Molishree Joshi
Administrator: Michaela Montour
Location: RC1 North: P18-6222, P18-6223
Services: shRNA, CRISPR, Plasmid, Genetic Screen, Cell-Engineering
Website: Functional Genomics
Gates Biomanufacturing Facility
Director: Matthew Seefeldt
Director: Terri Foote
Administrator: Charles Hickey
Location: Bioscience 1
Services: GMP manufacturing, Project management, Cell therapy, Recombinant protein, FDA compliance, Translational research
Website: Gates Biomanufacturing Facility
Gates Institute: Histology (Morphology & Phenotyping) Core
Director: Igor Kogut
Manager: Laura Hoaglin
Administrator : Carmen Garcia
Location: P15-4430A
Services: Histology, Tissue grossing, Embedding, Paraffin Processing, Sectioning (paraffin/OCT), Automated Immunohistochemistry & Immunofluorescence
Website: The Gates Center Histology Core
Gates Institute: Stem Cell Biobanking & Disease Modeling Core (SCB&DM)
Director: Ganna Bilousova
Director: Igor Kogut
Manager: Michael Ferreyros
Administrator: Carmen Garcia
Location: P15-4410A
Services: Cell Reprogramming and iPSC Characterization, Gene editing of iPSCs, Production of modified mRNA, Biobanking
Website: The Gates Center Stemcell Biobanking & Disease Modeling Core
Genetically Engineered Murine Models (GEMM) Core
Director: Jennifer Matsuda
Administrator: Bernadine Sena
Location: National Jewish Hospital
Services: Transgenic, Knockout, CRISPR/Cas9, Rederivation, Cryopreservation
Genomics and Microarray Shared Resource (GSR) at the CU Cancer Center
Director: Bifeng Gao
Manager: Nicole Manning
Administrator: Michaela Montour
Location: RC2: P15-9400
Services: Next Generation Sequencing; Single Cell Sequencing; Spatial Transcriptomics; Microarray; Experimental Consultation
Website: Genomics Shared Resource
Gnotobiotic Core
Director: Jordi Lanis
Technician: Kaitlyn Cox
Location: Vivarium
Services: Germ free, Gnotobiotic, Microbiome
Website: Gnotobiotic Core
HI3 Cores: Human Immune Monitoring Shared Resource (HIMSR)
Director: Jill Slansky
Assistant Director: Kimberly Jordan
Administrator: Lanette Schwarz
Location: RC1 North: P18-8113, P18-8403, P18-8202, P18-8212, P18-8206
Services: Immunotherapy, Immunology, Sample processing of clinical sample, Cytokines, Cytof, Mass cytometry, Flow cytometry, Imaging, Immunohistochemistry, IHC, Immunofluorescence, ELISA, Multiplex, MIBI, MSD (mesoscale discovery), Cytech, Polaris, Vectra, Phenotyping, inform, Flowjo, Blood Samples, PBMC, Plasma, Serum, Smart Tube Technology, Lymphocytes, Tissue Microscopy, Biomarker
Core-Specific Equipment: Akoya PhenoImager HT, 10x Genomics Xenium, Spatial transcriptomics, Spatial proteomics, Multi-omics, Histology, RNAscope
Website: The Human Immune Monitoring Shared Resource at CU|AMC
HI3 Cores: Pre-clinical Human Immune System Mice Share Resource (PHISM)
Director: Roberta Pelanda
Co-Director: Julie Lang
Location: RC1 North: P18-8404G and P18-8132
Keywords: Humanized, Mice, Immunotherapy, In-Vivo, Pre-Clinical
Website: Pre-clinical Human Immune System Mouse model and Analysis Shared Resource
Irradiation Sciences Core at the CU Cancer Center
Director: David Westerly
Manager: Tyler Weiskopf
Location: RC1 North: Vivarium, P18-0437
Services: Image-guided irradiator, Precision x-ray, Animal tumor irradiation, Immune function assays, Radiation-induced DNA damage
Website: Irradiation Services
Islet Preparation Core at the Barbara Davis Center
Manager: Scott Beard
Location: BDC, 4th Floor, Room 4209
Keywords: Pancreatic Islets, Rodent Islet Isolation, Islet / Tissue Transplantation (kidney capsule), Pancreas Inflation Training, Human Islet Distribution
Website: Pancreatic Islet Preparation Core
Neurotechnology Center (NTC): Advanced Light Microscopy Core (ALMC)
Director: Richard Benninger
Manager: Radu Moldovan
Administrator: Paula Robinson
Location:
Currently:
RC1 North: 7th Floor and 8th Floor
RC2: 7th Floor RC1 South: 11th Floor
Fall 2021:
RC1 North: 1st Floor
RC2: 7th Floor
RC1 South: 11th Floor
Services: Imaging, Fluorescence, Confocal microscopy, Super-resolution microscopy
Website: Advanced Light Microscopy
Neurotechnology Center (NTC): Animal Behavior Core
Director: Michael Mesches
Manager: Nicolas Busquet
Administrator: Paula Robinson
Location: RC1 North, R2, AHSB: Vivarium
Keywords: Rodent Behavior Testing; Animal models; Cognition, learning, and memory; Stress, anxiety, and depression; Sensory and motor function; Behavioral phenotyping
Website: Animal Behavior Core
Neurotechnology Center (NTC): In Vivo Neurophysiology (EEG)
Director: Michael Mesches
Administrator: Paula Robinson
Location: AHSB: Vivarium
Services: EEG, EMG recording, Sleep architecture, Stereotactic surgery, Electrode manufacture and implantation, Rodent in vivo neurophysiology
Website: In Vivo Neurophysiology (EEG)
Neurotechnology Center (NTC): Machine Shop
Director: Gidon Felsen
Administrator: Paula Robinson
Location: Fitzsimons: Q20-NG003 and Q20-NG003B
Services: Experimental device design. Machining, Prototyping, Fabrication, Maintenance and repair of laboratory equipment
Core-Specific Equipment: - Manual Milling Machines (One with Digital Readout) - Full 3-Axis Automation CNC Milling Machine - Laser Cutter / Engraver - Large-Format Dual-Head FFF 3D Printer - Metal Lathes (One high-precision)? - Wood / Metal-Cutting Band Saws - Table Saw - Panel Saw - Precision Surface Grinder - Drill Press - 12" disk sander, 6" belt sander - Shearing, Bending, Pressing Equipment - Extensive Tooling & Precision Measuring Devices
Website: Machine Shop
Neurotechnology Center (NTC): Optogenetics & Neural Engineering Core (ONE)
Director: Gidon Felsen
Manager: Andrew Scallon
Administrator: Paula Robinson
Location: RC1 North: P18-7113 and P18-7401L
Services: Optics, Electronics, Custom engineering, 3D printing and design, Neural data analysis
Neurotechnology Center (NTC): The Innovation and Design for Experimentation and Analysis (IDEA) Core
Director: Gidon Felsen
Manager: Ryan Williamson
Location: RC1 North: P18-7107
Services: Engineering, Neuroscience, Data Analysis, Instrument Design, Animal Behavior
Website: The IDEA Core
Nutrition Obesity Research Center (NORC): Clinical Intervention and Translation (CIT) Core
Director: Janine Higgins
Location: Anschutz Health and Wellness Center
Keywords: Weight loss, Diet, Nutrition, Food intake, Appetite regulation
Nutrition Obesity Research Center (NORC): Energy Balance Assessment (EBA) Core
Director: Wendy Kohrt
Associate Director: Edward Melanson
Associate Director: Paul MacLean
Location:
RC1 North: P18-5402, F, G, J, L, K, M, P18-5207, P18-5208
Leprino Building: 3rd Floor
Keywords: Body composition, Energy expenditure, Resting metabolic rate, Physical activity, Exercise
Core-Specific Equipment: High-Resolution peripheral Quantitative Computed Tomography imaging device (HR-pQCT)
Website: Energy Balance Assessment Core
Nutrition Obesity Research Center (NORC): Molecular and Cellular Analytical (MCA) Core
Director: Bryan Bergman
Associate Director: Kartik Shankar
Managing Director: Matthew Jackman
Location:
RC2: 5th Floor
RC1 South: L18-6207 and L18-7403E
Keywords: Lipidomic, Mass Spectrometry, Mitochondrial Function, RNAseq
OLAR (Office of Laboratory Animal Resources)
Director: Jori Leszczynski
Administrator: Carolyn Russell
Location:
RC1 North: Vivarium
RC2: Vivarium
Fall 2021: AHSB Basement BDC, CU Denver Science Building basement, Denver Health, and Perinatal Research
Services: Animals, Husbandry, Veterinary Care, Breeding, Surgery, Comparative Clinical Pathology, Necropsy Services, Technical Services/Investigator Support, IACUC Protocol Consultation and Planning, Training -- Handling, Experimental Procedures
Organoid and Tissue Modeling Shared Resource (OTMSR)
Director: Peter Dempsey
Manager: P. Sean McGrath
Administrator : Robert Murchison
Location: Barbara Davis Center, 3rd Floor, Room(s) M20-3202P, 3205, 3203
Services: Adult- and iPSC-derived 3D organoid models (human & mouse), conditioned media, matrices and reagents for 3D culture, gene editing (point mutations and fluorescent knock-in), organoid assays and imaging, biobanking
Website: Organoid and Tissue Modeling Shared Resource (OTMSR)
Pathology Shared Resource (PSR) at the CU Cancer Center - Cytogenetics
Director: Liming Bao
Manager: Mary Haag
Administrator: Michaela Montour
Location: Biosciences 2, Suite 400
Services: Chromosome/Karyotype Analysis, Fluorescence in situ Hybridization (FISH), Chromosomal Microarray (CMA)
Website: Pathology Shared Resource
Pathology Shared Resource (PSR) at the CU Cancer Center - Molecular Testing
Director: Dara Aisner
Manager: Kurtis Davies
Administrator: Michaela Montour
Location: Biosciences 2, Suite 400
Services: Targeted NGS, Precision Medicine, FFPE Sample Processing, Mutation Analysis, Gene Fusion
Website: Pathology Shared Resource
Pathology Shared Resource (PSR) at the CU Cancer Center - Research Histology
Directors: M. Scott Lucia and Adrie vanBokhoven
Manager: E. Erin Smith
Administrator: Michaela Montour
Location: RC1 North: P18-5220, P18-5221^02
Services: Histology, Tissue grossing/cassetting, Paraffin processing, Sectioning, Routing and staining, Immunohistochemistry, Antibody optimization
Website: Pathology Shared Resource
Pre-Clinical Cardiovascular Core
Principal Investigator: Tim McKinsey
Director: Maria Cavasin
Administrator: Kelley Brodsky
Location: RC2: 8th floor; RC2: vivarium
Keywords: Fibrosis, Pre-clinical studies, In vivo fibrosis models, ECHO imaging, Novel therapies
Website: Pre-Clinical Cardiovascular Core
Research Informatics Office: Health Data Compass
Director: Ian M. Brooks, PhD
Administrator: Sarah Ayala
Location:
Fitzsimons: 5th floor East, CCPM/HDC
Fall 2021: AHSB
Services: Clinical Data, Informatics, Data Science, Genomics, Clinical Data Warehouse
Website: Health Data Compass
School of Medicine Metabolomics Core (part of the CU Cancer Center Mass Spectrometry Shared Resource - MSSR)
Director: Angelo D'Alessandro
Manager: Julie Reisz Haines
Administrator : Shelly Fortner
Location: RC1 South: L18-1303
Services: High Throughput Metabolomics, In Vitro and In Vivo Stable Isotope Tracing, Absolute Quantitation, Polar Lipidomics, Trace Metal Analysis
Website: School of Medicine Metabolomics Core
School of Medicine Proteomics Core (part of the CU Cancer Center Mass Spectrometry Shared Resource - MSSR)
Director: Kirk Hansen
Manager: Anthony Saviola
Administrator : Shelly Fortner
Location: RC1 South: L18-1303
Services: Global Proteomics, Deep Proteomics, Absolute Quantitation, Post-translational Modifications, Protein Identification
Website: School of Medicine Proteomics Core
School of Pharmacy Resources: Computational Chemistry and Biology Core
Director: Philip Reigan
Location: School Of Pharmacy: V20-2104
Services: Molecular modeling, Protein Modeling, Drug Design, Structure-Activity Relationship
School of Pharmacy Resources: Medicinal Chemistry Core Facility
Director: Michael Wempe
Manager: Vijay Kumar
Administrator: Peggy McIntosh
Location: School Of Pharmacy: V20-2410
Services: Chemical Synthesis, LC/MS-MS, HPLC/UV, NMR, Preclinical Safety Assessment
Website: Medicinal Chemistry
School of Pharmacy Resources: SSPPS Mass Spectrometry Facility
Director: Nichole Reisdorph
Assistant Director: Richard Reisdorph
Location: School Of Pharmacy: V20-2260 and V20-2460
Services: Metabolomics, Proteomics, Acetylomics, Lipidomics, Targeted mass spectrometry
Website: Mass Spectrometry Facility
Structural Biology: Biophysics
Director: Julie Cooper
Manager: Robb Welty
Administrator : Shelly Fortner
Location: RC1 South: L18-2400, L18-2400B, L18-2400D, L18-2400E
Services: Molecular interactions, Quantitative analysis, Biophysics, Macromolecular structure, RNA/DNA/Protein complexes
Website: Biophysics Shared Resource Facility
Structural Biology: CryoElectron Microscopy (CryoEM)
Director: Francisco Asturias
Manager: John Hardin
Administrator : Shelly Fortner
Location: RC1 South: L18-1302, L18-1302A, L18-1206, L18-1207F
Services: Cryo-EM, Macromolecular structure, Protein/RNA/DNA complexes, Macromolecular Interactions, Conformational changes
Website: Cryo-EM Structural Biology Shared Resource Facility
Structural Biology: Nuclear Magnetic Resonance (NMR)
Director: David Jones
Co-Director/Manager: John Hardin
Administrator : Shelly Fortner
Location: RC1 South: L18-1300
Services: NMR spectroscopy, Macromolecular structure, Molecular interactions, Drug screening, Macromolecular motions
Structural Biology: X-Ray Crystallography
Director: Mair Churchill
Manager: John Hardin
Administrator : Shelly Fortner
Location: RC1 South: L18-1201, L18-1201A, L18-1201B, L18-1201C, L18-1301, L18-1202
Services: Macromolecular crystallography , Structural biology, Drug-receptor interactions, Synchrotron data collection, DNA/RNA/protein