Research Core Labs

Researchers in lab

One of the defining features of a top-tier research university is the availability of core facilities that provide a spectrum of contemporary analytic tools that can be shared across the campus. Ideally these cores provide both technical and consultative services at mode​st cost and, as a result, elevate the quality of the overall research enterprise. It is appropriate that the core landscape evolves as new technologies emerge and others become obsolete.

Below is a list to the current operational research cores supported by the School of Medicine and the research leadership on the Anschutz Medical Campus.


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e.g., biomarker, data analysis, flow cytometry, genetic screen, proteomics

Core Labs

(Showing all 48 labs)(Clear Search Results)

Allergy and Clinical Immunology Core

Director: Brent Palmer

Technical Director: Charles Preston Neff

Location: RC2, 10th Floor, Room 10231 and 10232

Services: Flow Cytometry, Cellular Immunology, Cell Analysis and Sorting, Monoclonal Antibody Panel Design, Data Analysis

Website: ClinImmune, Allergy & Clinical Immunology, Infectious Disease Flow Cytometry & Bioarchiving Facility

Animal Imaging Shared Resource (AISR) at the CU Cancer Center

Director: Natalie Serkova

Manager: Jenna Steiner

Administrator: Michaela Montour

Location:

RC1 North: Vivarium, P18-0434, P18-0443
RC2: P15-1109, P15-1306, P15-1214

Services: Magnetic Resonance Imaging (MRI), IVIS Imaging, Bioluminescence, Computed Tomography (CT), FDG-PET

Website: Animal Imaging Shared Resource

Autoantibody/HLA Core Facility

Director: Liping Yu

Administrator: Allison Reeds

Location: Barbara Davis Center: M20-4201A-H

Keywords: Autoantibodies, HLA, Type 1 diabetes, Celiac disease, Biomarker

Website: Autoantibody/HLA Core Facility

Biostatistics & Bioinformatics Shared Resource (BBSR) at the CU Cancer Center

Location:

Fitzsimons: Q20-N2211, Q20-N2215, Q20-N2227C^02, Q20-N6203D, Q20-N6203E, Q20-W3127^02
RC1 South: L18-5113^02

Services: Biostatistics, Bioinformatics, Study design, Data analysis, -omics, Clinical trials

Website: Biostatistics and Bioinformatics Shared Resource

Cardiovascular Bioimaging Core: CTRC Outpatient Clinic

Director: Kerrie Moreau

Administrator: Tim Lockie

Location: Leprino Building: 3rd Floor - CTRC Outpatient

Services: Ultrasound, Cardiac, Vascular, Liver, Fibroscan

Website: Clinical and Translational Research Centers (CTRC)

Cell Technologies Shared Resource (CTSR)

Directors: Steven M. Anderson and Peter Dempsey

Manager: Lori Sherman

Location: RC1 South: L18-5404B

Services: Hybridoma/Monoclonal antibody, Fetal calf serum, Cell lines, Protein expression, IncuCyte

Website: Cell Technologies Shared Resource

Center for Innovative Design and Analysis (CIDA) - Consulting Center

Director: Nichole Carlson (CSPH)

Consulting Center Manager: Camille Hochheimer

Administrator: Theresa Jennings

Location: Fitzsimons: 4th Floor West

Services: Data Analysis, Grant Development and Study Design, Data Science, Biostatistics, Long/Short-Term Partnerships

Website: Center for Innovative Design & Analysis

Clinical Research Support Services (CREST)

Director: Aaron Mobley

Location:

Leprino Building: 3rd Floor
Fall 2021: Fitzsimons Building, TBD

Services: Clinical Coordinators & Coordination, Clinical Monitoring, IRB & Regulatory Assistance, Study Startup & Administration Help, OnCore Submission & Signoff Help, Sponsor Invoicing, Invoice Payments

Website: Clinical Research Support Team (CReST)

Colorado Anschutz Research Genetics Organization (CARGO): Colorado Center for Personalized Medicine

Principal Investigator: Kathleen Barnes

Director: Monica Campbell

Project Managers: Meher Boorgula, Nicholas Rafaels

Administrator: Alesia El Ali

Location: RC2: P15-3490B, P15-3490C, P15-3490F

Services: DNA/RNA Services, Genotyping, Data Analysis

Website: Colorado Anschutz Research Genetics Organization (CARGO)

Colorado Center for Personalized Medicine: Health Data Compass

Director: Ian M. Brooks, PhD

Administrator: Sandra Logue

Location:

Fitzsimons: 5th floor East, CCPM/HDC
Fall 2021: AHSB

Services: Clinical Data, Informatics, Data Science, Genomics, Clinical Data Warehouse

Website: Health Data Compass

Colorado Clinical and Translational Sciences Institute (CCTSI) Clinical Research Core: Adult CTRC Core Laboratory

Director: Pamila Allen

Assistant Director: Karen Morgenthaler

Administrator: Tim Lockie

Location:

Leprino Building: L10-326
Fall 2021: AHSB: Room 6110

Services: Research Laboratory, Analytical Testing, Chemistry Testing, Hormone/Peptide Testing, Cytokine Testing, Immunological Testing, HPLC, ELISA, RIA, COVID Testing, CAP and CLIA Accreditation Lab

Website: CTRC Services

Colorado Clinical and Translational Sciences Institute (CCTSI) Clinical Research Core: Biostatistics, Epidemiology, and Research Design (BERD)

Director: Nichole Carlson

Administrator: Theresa Jennings

Location: Fitzsimons: 4th Floor West

Services: Grant Development, Data Analysis, Statistical Education, Long/Short-Term Partnerships

Website: Biostatistics, Epidemiology and Research Design (BERD)

Colorado Clinical and Translational Sciences Institute (CCTSI) Clinical Research Core: CTRC Nutrition Services

Director: Janine Higgins

Manager: Tyson Marden

Administrator: Tim Lockie

Location:

Leprino Building: 3rd Floor
Fall 2021: kitchen in AHWC: 1st floor, office/clinic in AHSB: Room 6023

Services: Nutrition, Dietary intake, Metabolic meals, Diet design, Measurement of habitual dietary intake

Website: Nutrition Services

Diabetes Research Center Bioresources Core

Director: Lori Sussel

Administrator: Mark Farrell

Location: Barbara Davis Center: M20-4207 and M20-4209

Services: Islet isolation/function, Cytometry, Microscopy, Sanger sequencing, STR profiling

Website: Core Facilities

Drug Discovery and Development Shared Resource (D3SR) at the CU Cancer Center

Director, Arm 1: Dan LaBarbera (Drug Discovery and Hit-to-lead Drug Development)

Director, Arm 2: Dan Gustafson (In Vivo Pharmacology)

Location: Flint Animal Cancer Center, CSU School of Pharmacy

Services: Drug discovery, Pharmacokinetic and pharmacodynamic modeling, High throughput and high content sequencing, Compound libraries, Metabolism, Drug transporter studies

Website: Drug Discovery and Development

Electron Microscopy Center

Director: Anza Darehshouri

Administrator: Kate Beatty

Location: RC1 South 1207

Services: Electron microscopy, Project consultation, Sample preparation, Sample analysis, Training

Website: Electron Microscopy Center

Flow Cytometry Shared Resource at the CU Cancer Center

Director: Eric Clambey

Manager: Christine Childs

Administrator: Michaela Montour

Location: RC1 South: L18-4112, L18-4204, L18-4208, L18-4215, L18-4402G

Services: Flow cytometry, Cell sorting, CyTOF, Spectral flow cytometry, Mass cytometry

Website: Flow Cytometry

Functional Genomics Shared Resource (FGSR) at the CU Cancer Center

Director: Joaquin Espinosa

Manager: Molishree Joshi

Administrator: Michaela Montour

Location: RC1 North: P18-6222, P18-6223

Services: shRNA, CRISPR, Plasmid, Genetic Screen, Cell-Engineering

Website: Functional Genomics

Genomics and Microarray Shared Resource (GSR) at the CU Cancer Center

Director: Bifeng Gao

Manager: Katrina Diener

Administrator: Michaela Montour

Location: RC2: P15-9400A, P15-9400D, P15-9400B, P15-9400C, P15-9400E P15-9400F, P15-9410F P15-9420B^01, P15-9100-1, P15-9100

Services: Next Gen Sequencing (NGS), Genomics, MicroArrays, Single Cell Genomics, Spatial Genomics

Website: Genomics Shared Resource

Gnotobiotic Core

Director: Kristi Kuhn

Technician: Cassandra Levens

Location: Vivarium

Keywords: Germ free, Gnotobiotic

Website: Gnotobiotic Core

HI3 Cores: Human Immune Monitoring Shared Resource (HIMSR)

Director: Jill Slansky

Assistant Director: Kimberly Jordan

Administrator: Lanette Schwarz

Location: RC1 North: P18-8113, P18-8403, P18-8202, P18-8212, P18-8206

Services: Immunotherapy, Immunology, Sample processing of clinical sample, Cytokines, Cytof, Mass cytometry, Flow cytometry, Imaging, Uno histochemistry, IHC (Imm), Immune fluorescence, ELISA, Multiplex, MIBI, MSD (mesoscale discovery), Cytech, Polaris, Vectra, Phenotyping, inform, Flowjo, Blood Samples, PBMC, Plasma, Serum, Smart Tube Technology, Lymphocytes, Tissue Microscopy, Biomarker

Website: The Human Immune Monitoring Shared Resource at CU|AMC

HI3 Cores: Pre-clinical Human Immune System Mice Share Resource (PHISM)

Director: Roberta Pelanda

Assistant Director: Julie Lang

Location: RC1 North: P18-8404G and P18-8132

Keywords: Humanized, Mice, Immunotherapy, In-Vivo, Pre-Clinical

Website: Pre-clinical Human Immune System Mouse model and Analysis Shared Resource

Irradiation Sciences Core at the CU Cancer Center

Director: Sana Karam

Manager: David Westerly

Administrator: Michaela Montour

Location:

RC1 North: Vivarium, P18-0434, P18-0443
RC2: P15-1109, P15-1306, P15-1214

Services: Image-guided irradiator, Precision x-ray, Animal tumor irradiation, Immune function assays, Radiation-induced DNA damage

Website: Irradiation Services

Islet Preparation Core at the Barbara Davis Center

Manager: Scott Beard

Location: BDC, 4th Floor, Room 4209

Keywords: Pancreatic Islets, Rodent Islet Isolation, Islet / Tissue Transplantation (kidney capsule), Pancreas Inflation Training, Human Islet Distribution

Website: Pancreatic Islet Preparation Core

Mouse Genetics Core Facility (Transgenics)

Director: Jennifer Matsuda

Administrator: Bernadine Sena

Location: National Jewish Hospital

Services: Transgenic, Knockout, CRISPR/Cas9, Rederivation, Cryopreservation

Website: Mouse Genetics

Neurotechnology Center (NTC): Advanced Light Microscopy Core (ALMC)

Director: Richard Benninger

Manager: Radu Moldovan

Administrator: Paula Robinson

Location:
Currently:
RC1 North: 7th Floor and 8th Floor
RC2: 7th Floor RC1 South: 11th Floor

Fall 2021:
RC1 North: 1st Floor
RC2: 7th Floor
RC1 South: 11th Floor

Services: Imaging, Fluorescence, Confocal microscopy, Super-resolution microscopy

Website: Advanced Light Microscopy

Neurotechnology Center (NTC): Animal Behavior Core

Director: Michael Mesches

Manager: Nicolas Busquet

Administrator: Paula Robinson

Location: RC1 North: Vivarium

Keywords: Rodent Behavior Testing; Animal models; Cognition, learning, and memory; Stress, anxiety, and depression; Sensory and motor function; Behavioral phenotyping

Website: Animal Behavior Core

Neurotechnology Center (NTC): In Vivo Neurophysiology (EEG)

Director: Michael Mesches

Administrator: Paula Robinson

Location: RC1 North: Vivarium

Services: EEG, EMG recording, Sleep architecture, Stereotactic surgery, Electrode manufacture and implantation, Rodent in vivo neurophysiology

Website: In Vivo Neurophysiology (EEG)

Neurotechnology Center (NTC): Machine Shop

Director: Michael Hall

Administrator: Paula Robinson

Location: Fitzsimons: Q20-NG003 and Q20-NG003B

Services: Experimental device design. Machining, Prototyping, Fabrication, Maintenance and repair of laboratory equipment

Website: Machine Shop

Neurotechnology Center (NTC): Optogenetics & Neural Engineering Core (ONE)

Director: Gidon Felsen

Manager: Andrew Scallon

Administrator: Paula Robinson

Location: RC1 North: P18-7113 and P18-7401L

Services: Optics, Electronics, Custom engineering, 3D printing and design, Neural data analysis

Website: Optogenetics and Neural Engineering Core

Neurotechnology Center (NTC): The Innovation and Design for Experimentation and Analysis (IDEA) Core

Director and Manager: Ryan Williamson

Location: RC1 North: P18-7107

Services: Engineering, Neuroscience, Data Analysis, Instrument Design, Animal Behavior

Website: The IDEA Core

Nutrition Obesity Research Center (NORC): Clinical Intervention and Translation (CIT) Core

Director: Marc Cornier

Associate Director: Janine Higgins

Location: Anschutz Health and Wellness Center

Keywords: Weight loss, Diet, Nutrition, Food intake, Appetite regulation

Website: Clinical Intervention and Translation Core

Nutrition Obesity Research Center (NORC): Energy Balance Assessment (EBA) Core

Director: Wendy Kohrt

Associate Director: Edward Melanson

Associate Director: Paul MacLean

Location:

RC1 North: P18-5402, F, G, J, L, K, M, P18-5207, P18-5208
Leprino Building: 3rd Floor

Keywords: Body composition, Energy expenditure, Resting metabolic rate, Physical activity, Exercise

Website: Energy Balance Assessment Core

Nutrition Obesity Research Center (NORC): Molecular and Cellular Analytical (MCA) Core 

Director: Bryan Bergman

Associate Director: Kartik Shankar

Managing Director: Matthew Jackman

Location:

RC2: 5th Floor
RC1 South: L18-6207 and L18-7403E

Keywords: Lipidomic, Mass Spectrometry, Mitochondrial Function, RNAseq

Website: Molecular and Cellular Analytical Core

OLAR (Office of Laboratory Animal Resources)

Director: Jori Leszczynski

Administrator: Carolyn Russell

Location:

RC1 North: Vivarium
RC2: Vivarium
Fall 2021: AHSB Basement BDC, CU Denver Science Building basement, Denver Health, and Perinatal Research

Services: Animals, Husbandry, Veterinary Care, Breeding, Surgery, Comparative Clinical Pathology, Necropsy Services, Technical Services/Investigator Support, IACUC Protocol Consultation and Planning, Training -- Handling, Experimental Procedures

Website: Office of Laboratory Animal Resources (OLAR)

Organoid and Tissue Modeling Shared Resource (OTMSR)

Director: Peter Dempsey

Manager: P. Sean McGrath

Administrator : Robert Murchison

Location: Barbara Davis Center, 3rd Floor, Room(s) M20-3202P, 3205, 3203

Services: Adult- and iPSC-derived 3D organoid models (human & mouse), conditioned media, matrices and reagents for 3D culture, gene editing (point mutations and fluorescent knock-in), organoid assays and imaging, biobanking

Website: Organoid and Tissue Modeling Shared Resource (OTMSR)

Pathology Shared Resource (PSR) at the CU Cancer Center — Molecular Testing

Director: Dara Aisner

Manager: Kurtis Davies

Administrator: Michaela Montour

Location: Biosciences 2, Suite 400

Services: Targeted NGS, Precision Medicine, FFPE Sample Processing, Mutation Analysis, Gene Fusion

Website: Pathology Shared Resource

Pathology Shared Resource (PSR) at the CU Cancer Center — Research Histology

Directors: M. Scott Lucia and Adrie vanBokhoven

Manager: E. Erin Smith

Administrator: Michaela Montour

Location: RC1 North: P18-5220, P18-5221^02

Services: Histology, Tissue grossing/cassetting, Paraffin processing, Sectioning, Routing and staining, Immunohistochemistry, Antibody optimization

Website: Pathology Shared Resource

Pre-Clinical Cardiovascular Core

Principal Investigator: Tim McKinsey

Director: Maria Cavasin

Administrator: Kelley Brodsky

Location: RC2: 8th floor; RC2: vivarium

Keywords: Fibrosis, Pre-clinical studies, In vivo fibrosis models, ECHO imaging, Novel therapies

Website: In-Vivo Disease Modeling Unit

School of Medicine Metabolomics Core (part of the CU Cancer Center Mass Spectrometry Shared Resource — MSSR)

Director: Angelo D'Alessandro

Manager: Julie Reisz Haines

Admin/Finance: Sarah Gehrke

Location: RC1 South: L18-1303

Services: High Throughput Metabolomics, In Vitro and In Vivo Stable Isotope Tracing, Absolute Quantitation, Polar Lipidomics, Trace Metal Analysis

Website: School of Medicine Metabolomics Core

School of Medicine Proteomics Core (part of the CU Cancer Center Mass Spectrometry Shared Resource — MSSR)

Director: Kirk Hansen

Manager: Monika Dzieciatkowska

Admin/Finance: Sarah Gehrke

Location: RC1 South: L18-1303

Services: Global Proteomics, Deep Proteomics, Absolute Quantitation, Post-translational Modifications, Protein Identification

Website: School of Medicine Proteomics Core

School of Pharmacy Resources: Computational Chemistry and Biology Core

Director: Philip Reigan

Location: School Of Pharmacy: V20-2104

Services: Molecular modeling, Protein Modeling, Drug Design, Structure-Activity Relationship

Website: Computational Chemistry and Biology Core Facility

School of Pharmacy Resources: Medicinal Chemistry Core Facility

Director: Michael Wempe

Manager: Vijay Kumar

Administrator: Peggy McIntosh

Location: School Of Pharmacy: V20-2410

Services: Chemical Synthesis, LC/MS-MS, HPLC/UV, NMR, Preclinical Safety Assessment

Website: Medicinal Chemistry

School of Pharmacy Resources: SSPPS Mass Spectrometry Facility

Director: Nichole Reisdorph

Assistant Director: Richard Reisdorph

Location: School Of Pharmacy: V20-2260 and V20-2460

Services: Metabolomics, Proteomics, Acetylomics, Lipidomics, Targeted mass spectrometry

Website: Mass Spectrometry Facility

Structural Biology: Biophysics

Director: Jeffrey Kieft

Admin/Finance: Sarah Gehrke

Manager: Jared Lindenberger

Location: RC1 South: L18-2400, L18-2400B, L18-2400D, L18-2400E

Services: Molecular interactions, Quantitative analysis, Biophysics, Macromolecular structure, RNA/DNA/Protein complexes

Website: Biophysics Shared Resource Facility

Structural Biology: CryoElectron Microscopy (CryoEM)

Director: Jeffrey Kieft

Admin/Finance: Sarah Gehrke

Co-Director: Francisco Asturias

Manager: Eduardo Romero-Camacho

Location: RC1 South: L18-1302, L18-1302A, L18-1206, L18-1207F

Services: Cryo-EM, Macromolecular structure, Protein/RNA/DNA complexes, Macromolecular Interactions, Conformational changes

Website: Cryo-EM Structural Biology Shared Resource Facility

Structural Biology: Nuclear Magnetic Resonance (NMR)

Director: Jeffrey Kieft

Admin/Finance: Sarah Gehrke

Co-Director/Manager: David Jones

Location: RC1 South: L18-1300

Services: NMR spectroscopy, Macromolecular structure, Molecular interactions, Drug screening, Macromolecular motions

Website: NMR Structural Biology Shared Resource Facility

Structural Biology: X-Ray Crystallography

Director: Jeffrey Kieft

Admin/Finance: Sarah Gehrke

Co-Director: Mair Churchill

Manager: John Hardin

Location: RC1 South: L18-1201, L18-1201A, L18-1201B, L18-1201C, L18-1301, L18-1202

Services: Macromolecular crystallography , Structural biology, Drug-receptor interactions, Synchrotron data collection, DNA/RNA/protein

Website: X-ray Crystallography Shared Resource Facility